Tizin - official instructions for use. Vasoconstrictor drug Tizin: release forms and instructions for use

03.04.2019

Tizin is a vasoconstrictor drug, produced in the form of drops and sprays, and is intended for the treatment of the runny nose and its complications in the form of rhinitis, sinusitis, pharyngitis, and sinusitis. The drug belongs to pharmacological group alpha-agonists. Their main purpose is to enhance the effect of adrenaline in the human body.

Effect of the drug

By increasing adrenaline, the drug has an active therapeutic effect, eliminating the symptoms of a runny nose. It is effective not only for viral and bacterial rhinitis, but also for diseases caused by allergic reaction body. The use of Tizin, according to the instructions, is allowed in the treatment of adults and children from the very beginning. early age. Drops and spray are low toxic, and their therapeutic result– instant and sustainable.

Active substance– xylometazoline, works as an alpha-adrenergic agonist and has a vasoconstrictor effect. And the vasoconstrictor effect after instillation of drops or irrigation of the nasal cavity is achieved in a short time. Tizin spray and nasal drops retain their effect for up to 8 hours.

Tizin is also used to treat conjunctivitis

Compared to nasal medications of the previous generation, Tizin is endowed with many obvious advantages, which many specialists - allergists, otolaryngologists, therapists and pediatricians - have long talked about.

According to the instructions, the drug is prescribed for the following indications:

  • secondary hyperemia against the background allergic diseases eye;
  • swelling of the conjunctiva;
  • catarrhal conjunctivitis;
  • irritation of the conjunctiva.

In addition, after reading the reviews of users and the specialists themselves, the effectiveness of Tizin for diseases such as:

  • pharyngitis;
  • rhinitis;
  • hay fever;
  • sinusitis.

This drug is often prescribed before scheduled diagnostic or therapeutic measures when you need to eliminate nasal swelling.

The onset of action is usually observed within 10 minutes after application of the product. Tizin reduces swelling and improves nasal breathing. When using drops or spray for nasal congestion due to the accumulation of mucus in it, the secretion of secretions improves. In the case when a person suffers from increased mucus production, its amount decreases.

Features of application

Tizin is intended for the treatment of nasal diseases and their complications in patients starting from the age of 2 years. For children of this age, a medicine of 0.05% is used, after 6 years - a 0.1% solution. When using the spray, children irrigate the nasal passages once, or instill 2-3 drops.

It is forbidden to take Tizin for more than 3 to 5 days, since this drug belongs to the group of vasoconstrictors. More long-term treatment allowed only as prescribed by a doctor and only under his supervision.

In some cases it is allowed re-treatment with the help of Tizin, but only through certain time and after consulting a doctor.

When leaking chronic rhinitis Tizin is not recommended for use as a therapeutic agent, because long-term use of the drug can lead to atrophy of the nasal mucous membranes.

Contraindications and side effects

There are certain contraindications that exclude the use of Tizin for a runny nose. This is, first of all, individual intolerance to the components of the spray or drops and childhood up to two years. Treatment with Tizin for dry runny nose, which is not accompanied by mucus, is also excluded.

Using an anti-rhinitis remedy according to the instructions almost never leads to side effects. The main thing is to accurately adhere to the dosage, dosage regimen and duration of use of Tizin indicated by your doctor.

If patients exceed the dosage or the permissible period of treatment with this vasoconstrictor, burning and excessive dryness of the mucous membranes may occur. In this case, patients, in addition to dryness and burning, complain of constant sneezing and copious discharge of mucous secretion from the nose.

In rare cases, as a result of an overdose or intolerance to the components of the drug, swelling of the nose may increase and the patient’s condition may worsen, which leads to the development of tachycardia, heart rhythm disturbances, increased blood pressure.

After reading the reviews of people for whom Tizin caused side effects, most often such signs of intoxication of the body were observed.

The therapeutic effect of Tizin drops occurs a couple of minutes after application and lasts for a long time - about 8 hours. The drug is popular in the treatment of pathologies of the ENT organs. The effect of the drug is due to the active substances included in its composition.

Compound

Tizin nasal drops contain tetrizoline hydrochloride as the active ingredient.

In 1 ml of product its volume is:

  • 0.5 mg tetrazoline (or 0.5% solution for children);
  • 1 mg (or 1% solution for adults).

Additional components of the medicine are benzyl alcohol, sorbitol, benzalkonium chloride, water and others.

Effect of the drug

Coming into contact with the mucous membrane of the nose and nasopharynx, the drops have an active symptomatic effect, successfully eliminating the symptoms of rhinitis. The drug works as an alpha-adrenergic agonist, simultaneously providing vasoconstrictor and decongestant effects. In a short period of time, a vasoconstrictor effect is achieved, which lasts up to 8 hours.

The composition of Tizin is highly effective not only for bacterial and viral origin, but also for allergic ENT pathologies that are extremely uncomfortable for a person.

Treatment with the drug, according to the instructions, is acceptable for both adults and children, starting from an early age. Tizin nasal drops are a low-toxic drug, and therapeutic effect, which they possess will be instantaneous and lasting.

Dosage forms

The drug is available in the following concentrations:

  • Nasal drops 0.1% volume 10 ml - for children over 6 years old and adults.
  • Nasal drops 0.05% volume 10 ml - for children.

Indications

The instructions for use indicate that Tizin is prescribed for following states and diseases:

The drug is also used during diagnostic and medical procedures, if it is necessary to eliminate swelling of the nasopharynx and normalize nasal breathing. It is not recommended to use nasal drops for more than 5 days, otherwise the patient may experience atrophy of the nasal mucosa.

Contraindications

Contraindications to the use of Tizin are as follows:

There are also age-related contraindications:

  • 0.05% the drug is not prescribed until the age of two;
  • The 0.1% drug is not recommended for children under 6 years of age.

Tizin is prescribed with caution when breastfeeding, during pregnancy, during endocrine disorders, diseases of cardio-vascular system. It is also recommended that people who drive vehicles and operate complex machinery be more careful.

Instructions

The drug is prescribed intranasally.

Tizin 0.05%, unless otherwise prescribed, is instilled in 2 drops for children from 2 to 6 years old.

The drug should be used strictly as needed, but not more than once every 4 hours. As a rule, these drops are used much less frequently, since their therapeutic effect lasts at least 8 hours. Using the product in the evening ensures a peaceful fall asleep and sleep throughout the night.

Tizin Bio

Tizin Bio - a vasoconstrictor used topically in otolaryngology.

The active ingredient of Tizin Bio is an alpha-adrenergic agonist - xylometazoline hydrochloride. Release form: spray. The drug narrows blood vessels nasal mucosa, eliminates swelling and hyperemia, restoring nasal breathing during rhinitis.

Hyaluronic acid in Tizin Bio creates a feeling of hydration and helps speed up the process of restoration of mucous membranes damaged during the disease.

According to the instructions for use, Tizin Bio spray is prescribed for acute rhinitis, allergic rhinitis, hay fever. The drug also helps remove mucus from sinusitis.

Tizin Allergo

Tizin Allegro - antiallergic drug local application. The active component of the drug - levocabastine hydrochloride - has an effect on histamine receptor blockers.

After a short course of treatment with the drug, the patient’s symptoms disappear allergic rhinitis: disappear copious discharge from the nasal cavity and swelling of the nasopharynx.

Indications for use of Tizin Allergo:

  • allergic rhinitis;
  • exacerbation of hay fever in the phase of rhinoconjunctival syndrome;
  • allergic conjunctivitis.

Tizin for allergies is available in the form of a spray. The drug has quick effect, eliminates the symptoms of allergic rhinitis and improves the patient’s quality of life.

Tizin for children

The drug 0.1% concentration cannot be used to treat children under 6 years of age.

Before using nasal drops, you should always consult your doctor.

Tizin for pregnant women

According to the instructions for use, Tizin drops or spray should be prescribed to expectant mothers with caution in cases where the use of this remedy simply cannot be avoided. But only a doctor can prescribe the drug, who will monitor the condition of the woman and fetus during the treatment process.

In other cases, Tizin is contraindicated for pregnant women, since there is no accurate information about the safety of treatment with this drug and its effect on the fetus.

If there is a need to use Tizin during lactation, then it is advisable to switch the baby to artificial formulas for the period of treatment.

Side effects

Side effects of Tizin and Tizin Bio include:

  • from the nervous system - drowsiness, general weakness, dizziness, migraine, tremor, sleep disorders;
  • from the heart and blood vessels - cardiac dysfunction, increased blood pressure;
  • from the outside endocrine system- hyperglycemia;
  • from the digestive system - nausea, heartburn;
  • from the respiratory system - burning and dryness in the nasal cavity, sneezing, secondary swelling of the mucous membrane as a result of exceeding the dose of the drug or with prolonged use;
  • from the organs of vision - increased intraocular pressure, dilation of the pupil.

Overdose


In case of an overdose of Tizin, the following symptoms may occur:

  • nausea;
  • dilated pupils;
  • heart rhythm disorders;
  • increased blood pressure;
  • pulmonary edema;
  • mental disorders;
  • increased drowsiness;
  • state of shock;
  • respiratory arrest;
  • coma.

The drug does not have an antidote. In case of overdose, Physostigmine is prescribed as first aid if anticholinergic symptoms occur. Activated carbon, symptomatic therapy, in extreme cases - gastric lavage and artificial oxygen supply.

Analogues

You can replace Tizin with the following drugs:

  • Nazivin. Nasal remedy group of alpha-adrenergic agonists, widely used in ENT practice. Release form: spray or drops. The active ingredient is oxymetazoline hydrochloride, which has a vasoconstrictor and anti-edematous effect. Nazivin, as an analogue of Tizin, is prescribed for the treatment of acute and allergic rhinitis, eustachitis, etc.
  • . Medicine based on a vasoconstrictor component, used in otolaryngology to treat runny nose. Release form: spray and drops. The active ingredient is xylometazoline. The drug is prescribed for acute rhinitis, including allergic origin, sinusitis and otitis media.

Tizin, like any drug, contains chemical substances, to which, if their concentration is unjustifiably exceeded, the body can react unpredictably.

Useful video about the use of vasoconstrictor drops

With a severe runny nose, we are looking for a remedy that would stop the incessant nasal discharge, make breathing easier, relieve congestion, and promote calm. inflammatory process in the nasal sinuses. If you look at consumer reviews, it is noticeable that it is enough big number people chose this medicine "Tizin". Instructions for using its “Classic” and “Xylo” forms for adults and children are waiting for you in this article. Let's look at the composition, indications, contraindications, side effects and so on.

"Classic": composition

First of all, the instructions for “Tizin” introduce us to the composition of the product:

  • Main active ingredient- xylometazoline hydrochloride. 1 ml contains either 1 mg (0.1%) or 0.5 mg (0.05%) of this substance.
  • Auxiliary elements are sorbitol, sodium chloride, benzalkonium chloride, disodium edetate, purified water for solutions.

By appearance it is a colorless liquid, transparent to light. It has no odor or has a weak characteristic odor.

"Classic": properties of the drug

The instructions for "Tizin" explain that medicinal properties solutions are based on the action of xylometazoline. By its nature, the component will be an imidazole derivative. Xylometazoline has alpha-adrenergic activity. It is noted that this symptomatic remedy(that is, it is aimed only at eliminating symptoms).

Xylometazoline has a vasoconstrictor effect. The medicine relieves swelling of the mucous membranes. The effect of its influence is felt after 5-10 minutes. Breathing relief occurs due to the reduction of hyperthermia and the removal of swelling of the mucous membranes of the nasal passages. Xylometazoline also promotes more active removal of mucus and other nasal secretions.

"Classic": indications for use

And again we will reveal the instructions for using Tizin. The indications here are related to conditions in which it is necessary to quickly relieve swelling of the mucous membranes of the nasopharynx and reduce the volume of secretions. In particular, this the following diseases:

It is also used to prepare the patient for diagnostic and surgical procedures on the nasopharynx.

Contraindications to the use of "Classic"

The instructions for the spray "Tizin" reveal the following contraindications for use this tool:

  • Individual intolerance, hypersensitivity to the active component and/or excipients.
  • Taking medications, drugs that can increase blood pressure.
  • Tachycardia.
  • Arterial hypertension.
  • Severe degree of atherosclerosis.
  • Rhinitis is atrophic.
  • Glaucoma.
  • Surgical operations in the anamnesis on meninges.

Instructions for using Tizin spray also impose some age restrictions:

Special instructions for using "Classic"

The manufacturer indicates that the classic Tizin spray should be taken with caution (consultation with your doctor is required) for the following pathologies, diseases and conditions:

  • Ischemic heart disease, angina pectoris.
  • Thyrotoxicosis.
  • Prostate hyperplasia.
  • Pheochromocytoma.
  • Forms of diabetes mellitus.
  • Hypersensitivity to adrenergic agonists, which is accompanied by dizziness and insomnia.

It is important to pay attention to the possibility of taking this drug for pregnant women. The instructions for "Tizin" (nasal spray) indicate that to date no clinical trials, confirming the complete safety of using the product for the fetus. Therefore, it is worth using "Tizin" when the benefit of treatment for the mother is assessed above the threat to the fetus.

It has also not been scientifically proven whether xylometazoline and its derivatives penetrate into breast milk. Therefore, during lactation women should use the spray with caution.

Application of "Classic", dosages for children and adults

The instructions for children's "Tizin" (concentration of the main component - 0.05%) show the following:

  • The drug is used to treat children 2-6 years old.
  • One dose of the product (one press on the cap) is administered into each nasal passage 1-2 times a day. Or according to the regimen prescribed by the attending physician.

Instructions for using the nasal spray "Tizin" for adults and children over 6 years old (concentration of the main component - 0.1%) are as follows:

  • One dose (one press of the cap) into each nasal passage 3 times a day.
  • The dosage may be changed as directed by the attending physician, due to hypersensitivity to individual components of the drug.
  • The maximum duration of use of the spray is 5-7 days (unless the doctor prescribes otherwise). The instructions for "Tizin" for children also advise you to always consult a pediatrician about the duration of the course of treatment with "Tizin".
  1. Remove the protective cap from the container.
  2. If the spray is used for the first time, then you need to press the spray head several times until a characteristic cloud of contents appears in the air.
  3. The product is sprayed into one nasal passage once.
  4. When using, hold the bottle vertically.
  5. When pressing the spray nozzle, try to inhale the contents at the same time.
  6. It is not recommended to spray the contents horizontally or downward.
  7. After using the product, it is closed with a cap and sent for storage in a dark, cool place where the drug will be inaccessible to small children and pets.

Side effects from "Classic"

Let's look at the reviews of those who have tried the drug, as well as the instructions for the spray. Side effects are indicated as follows:

  • Mild irritation of the nasal mucosa (slight burning), sneezing, paresthesia. In hypersensitive individuals, hypersecretion (excessive mucus production) is possible.
  • In a small percentage of cases, reactive hyperemia is noted. That is, increased swelling of the mucous membranes of the nasal passages.
  • Long-term use of the spray or its use in higher doses leads to dry mucous membranes, characteristic reactive stagnation, which leads to drug-induced rhinitis. The effect may last up to a week after completion of drug therapy. In rare cases, an overdose of Tizin leads to irreversible consequences- dry rhinitis (damage mucous membrane with the formation of crusts).
  • Very rare cases: insomnia, headache, depression, loss of strength. As a rule, this is noted only when long-term use medicines.
  • Isolated cases: arrhythmias, tachycardia, increased blood pressure, visual impairment.

"Xylo Bio": composition

Instructions for use of this form reveal the composition of the drug:

  • The active component is the same. This is xylometazoline hydrochloride. There are also two forms of release - with 0.1% (in 1 ml - 1 mg of the active element) and 0.05% (in 1 ml - 0.5 mg of the active element).
  • Excipients- sorbitol, glycerol, sodium hyaluronate, sodium chloride, purified water for solutions.

It is a clear, colorless (or slightly yellowish) liquid that is practically odorless.

"Xylo Bio": properties

As in the classical form, the main direction of influence is the removal of swelling of the mucous membrane of the nasal passages, as a result of which breathing becomes easier and nasal congestion goes away. Xylometazoline is also responsible for this effect.

In the form of "Xylo Bio" it also acts hyaluronic acid. It helps to moisturize the mucous membranes of the nose, keeping them hydrated, which has a beneficial effect on the healing process.

"Xylo Bio": indications for use

The scope of application of the Xylo Bio form will be as follows:

  • Relieving swelling of the mucous membranes of the nasopharynx during ARVI, rhinitis, hay fever, allergic rhinitis.
  • Facilitating the release of nasal secretions in case of paranasal sinusitis, colds and inflammation of the middle ear.

"Xylo Bio": contraindications

Contraindications to the use of this form are indicated as follows:

  • Intolerance to at least one of the components of the product.
  • Thyrotoxicosis.
  • Age up to 2 years.
  • Rhinitis is atrophic.
  • Heart and vascular diseases in severe form - severe atherosclerosis, arterial hypertension, angina pectoris, ischemic disease heart, tachycardia.
  • History of surgical operations on the meninges.

"Xylo Bio": special instructions for use

Like the classic form, Xylo Bio should be used with caution by pregnant and nursing mothers. Laboratory research To date, no studies have been carried out regarding the safety of use of the product for children.

With caution, after preliminary consultation with the treating doctor, the drug is taken for the following conditions and diseases:

  • When using medications that increase blood pressure.
  • With increased intraocular pressure(This is especially true for those suffering from narrow-angle glaucoma).
  • With pheochromocytoma.
  • For metabolic pathologies - diabetes mellitus, hyperthyroidism.
  • with prostatic hyperplasia.

Use of "Xylo Bio", dosages for children and adults

For children 2-6 years old, a form with a 0.05% concentration is indicated. active substance:

  • Frequency - 1-2 times a day.

Adults and children over 6 years old are shown a form with a 0.1% concentration of the active substance:

  • One dose (one spray) into each nasal passage.
  • Frequency - 3 times a day.

The duration of the course of treatment is no more than 5 days (unless the doctor prescribes otherwise).

Spray "Xylo Bio" is sprayed in exactly the same way as the classic form of "Tizin". In terms of side effects, it repeats the use of "Classic".

The spray preparation "Tizin" is available in two forms - "Classic" and "Xylo Bio". In turn, each drug is released into permissible concentration for children and adults. Reviews and instructions for "Tizin" speak of its excellent ability to quickly combat nasal congestion.

One of the many vasoconstrictor drugs that are widely used in ENT practice. Tizin has several release forms, which allows the patient to choose the most suitable suitable remedy. Approved for use in children.

Dosage form

Tizin is available in the form of drops. Bottle volume – 10 ml. The concentration of the active substance can be 0.05% and 0.1%. Pharmacies also stock the drug Tizin Xylo, which is available in the form of drops and spray. He has the same therapeutic effect, but contains a different active component.

Description and composition

Tizin drops are produced on the basis of tetrizoline. This active substance affects the alpha-adrenergic receptors of the sympathetic nervous system, which are located in the vessels of the nasal mucosa. After tetrizoline enters nasal cavity vasoconstriction occurs, which leads to the desired therapeutic effect.

Used for diseases that are accompanied by increased secretion secretion of the nasal cavity. It is a symptomatic treatment, facilitating the patient’s well-being and breathing. Vasoconstriction leads not only to a decrease in rhinorrhea, but also to a decrease in swelling of the mucous membrane.

The drug is applied topically, so its effect begins instantly. The effect is noticeable within a minute after using the drops. Duration of action – 4-8 hours. Tizin Xylo uses a more modern alpha-adrenergic agonist (), whose action lasts longer.

The drug acts only locally and is practically not absorbed into the systemic circulation when correct use. Increased absorption is possible in case of overdose or damage to the nasal mucosa.

Pharmacological group

Anticongestant. Vasoconstrictor. Alpha adrenergic agonist.

Indications for use

for adults

The drug is used in complex therapy:

  1. Rhinita.
  2. Sinusitis.
  3. Allergies.
  4. Respiratory diseases.
  5. Hay fever.

Tizin may also be given to reduce swelling and prevent bleeding before diagnostic measures or therapeutic manipulations.

for children

IN pediatric practice you need to select the dosage of the drug. From 2 years of age, Tizin concentration is allowed active component 0.05%, from 6 years old - with a concentration of 0.1%. The drug is not prescribed for children under 2 years of age.

Tizin is not recommended for use during pregnancy, since all drugs in this group can stimulate uterine contractions. In some cases, at the discretion of the doctor, Tizin may be prescribed to a pregnant woman in minimum dosage, since when correct use no systemic effect.

Contraindications

Contraindications to taking the drug are:

  1. Angle-closure glaucoma.
  2. Pregnancy.
  3. Hypersensitivity to any component of the drug.
  4. Age under 2 years.
  5. Dry or atrophic rhinitis.

Relative contraindications are hypertension and tachycardia, since exceeding the dose of Tizin can worsen the patient's condition.

Applications and dosages

for adults

The drug is taken intranasally. Before instilling Tizin, you need to tilt your head back slightly so that the medicine acts throughout the entire nasal passage. Single dose is 2 drops of a solution with a concentration of 0.1% in each nostril. It is not recommended to use the drug more than 4 times a day or longer than 5 days. Repeat course allowed after at least a week due to the fact that the active substance causes atrophy of the mucosa and it needs time to recover.

for children

In children, Tizin is used at a lower dosage. 2 drops of the drug are dripped into each nostril. It is not recommended to use the medicine for longer than 3 days. If Tizin is used at night, it may cause insomnia in some cases.

for pregnant women and during lactation

The use of the drug is allowed if potential benefit exceeds possible risk. Doctors usually recommend that pregnant women use a pediatric form of the drug with a lower concentration of the active ingredient. Must use it minimum rate and as few times a day as possible.

Side effects

Tizin drops may cause the following side effects:

  1. Burning.
  2. Hyperemia of the mucous membrane.
  3. Weakness.
  4. Headache.

Sometimes systemic reactions can be observed - tachycardia, sweating, increased blood pressure.

Interaction with other drugs

Concomitant use with drugs from the group of tricyclic antidepressants and monoamine oxidase inhibitors is not recommended. This interaction may result in increased blood pressure due to a vasoconstrictor effect.

special instructions

Patients with diseases of the cardiovascular system and metabolic disorders require a more thorough examination before prescribing the drug.

In some cases, Tizin causes visual impairment, so you should stop driving for the duration of treatment. vehicle and working with dangerous machinery.

Long-term use leads to atrophy of the mucous membrane, loss of smell, burning sensation and dryness in the nasal cavity.

Overdose

In case of overdose, the drug begins to have a systemic effect, which is manifested by the following symptoms:

  1. Pupil dilation.
  2. Cramps.
  3. Nausea.
  4. Hypertension.
  5. Tachycardia.
  6. Mental disorders.
  7. Pulmonary edema.
  8. Suppression of the nervous system - drowsiness, apnea, decreased body temperature.

There is no specific antidote. Treatment is symptomatic. After discontinuation of the drug, undesirable symptoms disappear fairly quickly.

Storage conditions

Tizin does not require special conditions storage Acceptable temperature regime- 25 degrees.

Analogues

There are many drugs available on the pharmaceutical market with similar action. They contain substances from the group of alpha-adrenergic agonists and are available in different dosage forms. Among them are the following:

  1. Nazalong. Available in the form of a spray with a concentration of active substance of 0.05%. Pharmacies have bottles of 10 and 25 g. The active ingredient is oxymetazoline, which is an alpha-adrenergic agonist. long acting. To eliminate nasal congestion and rhinorrhea, it is enough to use Nazalong 2 times a day.
  2. . Available in the form of drops and spray. Pharmacies also carry Sensitive, which is more suitable for allergy sufferers. The drug is intended for everyone age categories due to the fact that it has several dosages - 0.025%, 0.05% and 0.1%. Lowest dosage allowed from 1 year. The active ingredient is oxymetazoline.
  3. . Available in spray form. The active ingredient is oxymetazoline. Varieties:

The composition of Tizin nasal drops differs in the concentration of the active medicinal compound depending on the variety medicine.

In 1 ml. nasal drops (concentration 0.1%) contains 1 mg. tetrizoline hydrochloride , and in addition, such auxiliary components as: perfume oil, benzalkonium chloride, benzyl alcohol, disodium edetate, hydrochloric acid, sodium citrate, sorbitol, polyoxyethylene glycerol trihydroxystearate 40, water, sorbitol and methylhydroxypropylcellulose.

In 1 ml. Children's Tizin (concentration 0.05%) also contains 1 mg. medicinal compound and auxiliary components similar to the form of the drug described above.

Release form

Nasal drops are opalescent, colorless clear liquid, which is produced in specialized dropper bottles made of dark glass with a nominal volume of 10 ml. One package of Tizin contains only one bottle of nasal drops.

pharmachologic effect

Tizin belongs to a group of drugs that affect alpha adrenergic receptors and have anti-edematous and vasoconstrictive abilities .

Pharmacodynamics and pharmacokinetics

When using Tizin, drops narrow small in size arterioles located in nasal passages , while eliminating swelling of mucous tissues and reducing secretion . As a rule, the effect of using the drug occurs within one minute after its use and lasts for a maximum of 8 hours. It is noteworthy that these nasal drops are almost not absorbed.

Indications for use

This drug is indicated for use in , , as well as at . In addition, Tizin nasal drops are used as a preparatory agent before diagnostic or therapeutic manipulations in order to eliminate swelling of the mucous tissues of the nasal passages and nasopharynx.

Contraindications for Tizin

Contraindications to the use of the drug are: dry rhinitis , and . It is worth remembering that there is age restrictions on these nasal drops. For the treatment of children under 2 years of age, the drug should not be used, the concentration of the active compound in which reaches 0.05%. For patients under 6 years of age, the “adult” form of Tizin is contraindicated, i.e. drops 0.1%.

This medicine should be used with extreme caution in the treatment of patients suffering from diseases such as: IHD, hypertension, pheochromocytoma, and some others cardiovascular disorders and metabolic disorders .

Side effects

As a result of non-compliance with the recommendations for the use of the drug, the following side effects may occur: burning, hyperemia , with long-term use swelling of the mucous tissues of the nasal passages, tremor, palpitation, sweating, weakness And surges in blood pressure.

Instructions for use of Tizin (Method and dosage)

According to the instructions for Tizin, use nasal drops intranasally , i.e. instilled into the nasal passages with the head slightly tilted back. For adult patients and children over the age of 6 years, it is recommended to instill 2 or 4 drops of the drug, with a concentration of 0.1%, into each nostril.

Children's Tizin, with a concentration of 0.05%, is used in the treatment of children aged 2 to 6 years in a dosage equal to 2-3 drops. During pregnancy Tizin is used if the expected benefit is significantly greater than the harm. Nasal drops should be used no more than once every 4 hours.

As a rule, the drug has long-term exposure, so it is quite enough to use it infrequently. It should be remembered that maximum duration treatment with the drug should not exceed 5 days for adult patients and 3 days for children.
Although using drops before bed is considered effective measure to eliminate nasal congestion throughout the night, the drug can provoke the occurrence of nervous system person.

A second course of treatment with Tizin can be prescribed several days after the previous therapeutic treatment.

Overdose

In case of an overdose of Tizin, symptoms such as: cyanosis, dilated pupils, convulsions, nausea, fever, arrhythmia, hypertension, tachycardia, pulmonary edema, mental and respiratory disorders, cardiac arrest.

Interaction

Tizin should not be used in conjunction with tricyclic antidepressants , and also with monoamine oxidase inhibitors , since such a combination can have vasoconstrictor effect on the human body, and, in addition, influence the level.

Terms of sale

These nasal drops can be purchased at a pharmacy without a doctor's prescription.

Storage conditions

Tizin should be stored out of the reach of children at a temperature not exceeding 25 C.

Best before date

5 years. pregnancy and when used as nasal drops. In accordance with the instructions, the drug can be used by pregnant and nursing mothers only if the expected benefit is significantly higher than the possible harm.

Many people believe that children's Tizin can be used without fear during pregnancy and lactation, but this is not true, since when using both forms of the drug, life-threatening vasoconstrictor side effects can occur for both the mother and the child.

Tizin for children

For children, these nasal drops are not contraindicated, provided all recommendations are followed. Reviews of children's nasal drops are mainly positive character. average price for this type of medicine, as a rule, does not exceed 110 rubles.



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