How to remove uric acid from the body with medication. Review of drugs for removing uric acid in gout. Consequences and complications

14.02.2019

The article will talk about such a substance in the blood as uric acid. The norms, reasons for accumulation in tissues and ways to normalize the level in the body will be discussed.

Uric acid is a substance that is dissolved in blood plasma. This substance is formed as a result of the breakdown of protein, and is deposited in the human blood in the form sodium salt. Normal quantity uric acid is not harmful to health.

It is excreted from the body by the kidneys. The problem arises if this substance accumulates in the body. Then, uric acid can cause the development of serious chronic diseases.

To find out the amount of uric acid in the body, you need to take a blood test. You need to take the test in the morning, on an empty stomach. 2-3 days before the test, it is not recommended to consume excessively protein food and drink alcoholic beverages.

Functions of uric acid in the body

The normal level of uric acid must be present in the human body. After all, this substance performs several important functions:

it activates the production of adrenaline, thereby stimulating brain activity
Uric acid is a powerful antioxidant and prevents the development of cancer.

Uric acid levels in men, women and children

The amount of uric acid in the blood is determined at the genetic level and is inherited. But, as a rule, its ratio between the sexes is the same. In children, the uric acid level is the lowest, in women it is slightly higher, in men it is maximum.

A table that clearly demonstrates the level of uric acid

Causes of elevated uric acid levels in the blood

As noted above, uric acid is a breakdown product of protein. The body is designed in such a way that it is able to remove excess substances on its own. But when there are too many of them, the kidneys can no longer filter the blood properly. And uric acid begins to accumulate in tissues
The main reason for increased uric acid levels is poor nutrition. Protein foods should be consumed in moderation. Most of the diet should consist of foods rich in fiber: vegetables, fruits and cereals. If nutritional balance is disrupted, the body is not able to process all the protein and remove excess protein. As a result, the body is completely polluted
In some cases, increased uric acid levels may be caused due to stressful situations for the body: excessive physical exercise, fasting or alcohol abuse. Also, this substance begins to accumulate in tissues due to kidney dysfunction

Uric acid metabolism disorder

Eat medical term, which calls increased uric acid levels hyperuricemia. Therefore, all by-products contain preservatives. dyes, taste improvers and other synthetic additives will increase the level of uric acid and, of course, disrupt its metabolism.

Symptoms of high uric acid levels

Some symptoms indicate elevated uric acid levels.

When this substance accumulates in children, redness, eczema, and psoriasis are observed on the skin.
In adults and older people, severe pain occurs in the joints, on the skin, and wounds also appear. Men may experience severe pain in the groin, cystitis
Accumulation of uric acid leads to kidney disease and urinary system. Kidney stones are also actively formed due to hyperuricemia
Uric acid is also bad for teeth. Doctors note active tartar deposits and gum inflammation
Uric acid can deposit in the heart, causing pain and rapid heartbeat. In general, a person feels constant fatigue may suffer from insomnia

Salt deposition and the development of gout are closely related to increased level uric acid in the blood.

Reducing uric acid with folk remedies

If the first symptoms appear indicating an increase in uric acid levels, you should immediately consult a doctor. If the tests confirm suspicions, the doctor will prescribe a number of medications that will reduce the level of uric acid in the body. To support treatment, you can use traditional methods to reduce uric acid levels:

Visiting saunas and hot baths. If there are no contraindications, then visiting the sauna is great way remove excess substances through the skin. This will give your kidneys some rest.
Drink plenty of fluids. You can drink water without restrictions and green tea.
Decoctions of herbs and leaves. You should prepare a herbal mixture of dried birch, currant and lingonberry leaves, make a decoction and consume before meals
Herbal foot baths. If your joints hurt or sores appear on your legs, you can use warm foot baths with sage or chamomile. This will relieve inflammation and pain

The main remedy for normalizing uric acid levels is normalizing nutrition. To do this, along with treatment, you must follow a diet.

What removes uric acid from the body?

The kidneys are responsible for removing uric acid from the body. If this organ is unhealthy, then uric acid is not completely eliminated. It happens, on the contrary: the kidneys are healthy, but there is too much uric acid in the plasma, the kidneys cannot cope with the load.

One of the best ways remove excess uric acid, is drinking plenty of fluids. You need to drink water or green tea. You can add ginger and lemon to the water. At the same time, you need to reduce the amount of salt in your diet, because... salt retains fluids in the body.

Deposition of uric acid salts in joints

Elevated levels of uric acid can provide early warning of the development of cardiovascular disease. Therefore, it is recommended to take a blood test at least once a year.

How to reduce uric acid in gout?

Gout is an advanced form of arthritis. Diseases such as gout, osteochondrosis and arthritis develop due to the deposition of salts in the joints. Uric acid crystals, not finding a way out, are actively retained in the form of kidney stones and salts on the joints.

To reduce uric acid levels in gout, you need to follow a combination of remedies: apply medications prescribed by your doctor, follow a diet and use folk remedies.

Diet for high levels of uric acid in the blood

If you have hyperuricemia, you need to normalize your diet and, in future, not return to the old eating habits. During treatment, you should completely exclude the following foods from your diet:

beef
any fatty meat
liver, kidneys, brains
smoked fish and meat products, sausages
semi-finished products
rich broths
chocolate
confectionery with cream
alcohol

Foods that increase uric acid levels in the body

Uric acid is deposited in tissues due to too much protein in the diet. Protein, of course, should be present, but it is not recommended to eat protein foods at every meal.

Foods that can cause intense deposits of uric acid include: eggs, legumes, fatty and red meats, offal, sorrel. These foods should be consumed in moderation. From protein foods, preference should be given low-fat varieties meat (such as chicken and turkey).

Foods that reduce uric acid in the blood

It is necessary to reduce the consumption of eggs, legumes and mushrooms to a minimum. You need to eat a lot of vegetables, cereals, and bran bread. In general, products healthy fiber have a beneficial effect on the body
Doctors recommend one fasting day in Week. On this day you can eat one of the following products: kefir, cottage cheese, watermelons, apples, unsalted buckwheat. The product is divided into 5 equal portions and consumed throughout the day. You can drink green tea and water unlimitedly
If uric acid levels are elevated, you need to monitor water balance. Depending on weight, adults are recommended to drink 2 to 3 liters of water daily
Even when treatment is completed and prohibited foods can be eaten again, you should not return to your usual diet. This will again cause disturbances in the body

A person’s diet should have the following balance of foods: 50% - vegetables and fruits, 20% - meat and fish products, 20% - bread and cereals, 10% - fats and other substances.

Uric acid and the risk of heart disease

Sometimes, an increase in uric acid may indicate the presence of certain chronic diseases and cardiovascular diseases. Therefore, if hyperuricemia is detected, you should check for the following diseases:

gout
tuberculosis
pneumonia
leukemia
skin diseases (psoriasis, eczema)
liver and kidney diseases

How to reduce uric acid in the blood using folk remedies: tips and reviews

Daisies
Thyme
Immortelle
plantain

Video: Diet 6 for high uric acid

Video: Uric acid in joints

Gout is one of the common joint diseases, the development of which is caused by an excess of urates in the blood - uric acid salts, released during the breakdown of purines, which are elements of protein tissues. Crystallizing on the surface of the joints, urates injure them, causing severe pain when moving.

To reduce the level of uric acid, drugs of three types are used: uricodepressive - reducing the production of uric acid, uricosuric - increasing its removal from the body, and mixed. Among the agents that inhibit the synthesis of urates is vitamin B13, or orotic acid for gout, it is included in the complex pharmaceutical therapy diseases.

Principles of prescribing drugs

When a rheumatologist diagnoses a person with gout, next step becomes the determination of the type of disease. Depending on the factors that led to the imbalance purine metabolism, gout is divided into three types:

Metabolic – caused by metabolic disorders;
Renal - in this case the cause is a decrease in their normal function;
Mixed when both of these factors are present.

Lowering the level of urate in the blood can be achieved in two ways - by reducing the amount of uric acid produced by the body or by increasing its excretion - removal from the body. At increased secretion urate, genetically determined, primary gout is diagnosed. If the excess normal level uric acid is associated with a reduced degree of functioning internal organs– most often the kidneys, then gout is called secondary.

Gout often develops when both of these factors overlap. After determining whether the cause of excessive accumulation of urates in the blood is their hypersecretion or hypoexcretion, the doctor determines which drugs to reduce uric acid should be prescribed to the patient for treatment.

If a blood chemistry test shows elevated uric acid levels (hyperuricemia), but no external symptoms the development of gout is not observed, such drugs are not prescribed. They are prescribed only for frequent recurrence of attacks of gouty arthritis, as well as in the presence of signs confirming it chronic form– tophi. That's what they call painless subcutaneous seals near the joints affected by gout, containing a pasty mass of yellowish- white, which is crystallized urate.

Interesting!
During the period of exacerbation of the disease, drugs to remove uric acid from the body for gout are not taken. First, you should achieve a reduction in the severity of pain and inflammatory symptoms by taking non-steroidal anti-inflammatory drugs - NSAIDs.

Uricodepressants

The action of uricodepressants leads to a decrease in the synthesis of uric acid in the body. Allopurinol is one of the most popular drugs of this type. Its intake inhibits (reduces the activity) of the enzyme xanthine oxidase, under the influence of which hypoxanthine is converted into xanthine, and then into uric acid. The medicine is available in the form of tablets of 100 mg (50 pieces in one package) and 300 mg (30 pieces in one package).

The price of the drug ranges from 70 to 100 rubles per package, depending on the number of tablets in it. White tablets have a round or oval shape, divided in half by a score. One pill, in addition to the main active ingredient, contains a number of auxiliary substances that promote its better absorption:

Microcrystalline cellulose;
Edible gelatin;
Silica.

The dose for the treatment of gout is determined by the doctor. For an adult, the daily dose ranges from 100 to 900 mg, depending on the stage of development of the disease. The medicine is taken 2-4 times a day, after meals. The duration of treatment depends on the severity of the disease.

Among side effects Treatment with Allolpurinol is noted:

Increased blood pressure;
Bradycardia – slow heart rate;
Dizziness, headache;
Lethargy, drowsiness;
Impaired sense of taste.

At the beginning of the use of Allopurinol, due to the increased breakdown of urates crystallized on the surface of the joints, an increase in gout attacks is possible. Contraindications to its use are pregnancy, breast-feeding, renal and liver failure, individual intolerance substances included in the drug, and childhood.

Thiopurinol is another uricodepressant. It is an analogue of Allopurinol, having a similar effect and similar rules of administration, but is better tolerated by patients. Drug price in pharmacy chain– from 80 rubles.

Orotic acid, or vitamin B13. is a white powdery substance that is a product of wine production. B13 helps reduce urate levels in the blood by binding uric acid salts. The vitamin has double action– it combines the qualities of a urodepressant and uricosurite, which improves the excretion of urates from the body. Take 1 teaspoon three times a day before meals. The course of treatment for gout lasts 20 days, and after a three-week break is repeated. The effectiveness of orotic acid in the treatment of gout is much lower than that of Allopurinol and Thiopurinol, but the number of its contraindications is also much less - individual intolerance and allergic reaction. Therefore, vitamin B13 is often prescribed when it is impossible to use other uricodepressants. Thanks to this, as well as its low price (from 69 rubles), it is popular.

Interesting!
All of these drugs have a gradual effect, so they must be used for a long time. The total duration of the course of treatment is determined by the attending physician individually, depending on the patient’s condition and the body’s response to the use of drugs, and can take from several weeks to several months. While taking them, it is necessary to undergo periodic tests to monitor uric acid levels.

Uricosuric drugs

Experts also recommend treating gout with drugs that remove uric acid. This group of drugs includes drugs that have the property of reducing the formation and deposition of urate. articular surfaces due to the excretion of uric acid through the kidneys. Tablets for removing uric acid for gout include:

Fullflex is available in the form of oral (intended to be swallowed) capsules and ointment for external use. Active substances Fulflexa is an extract of Martinique aromatic root and white willow bark. The first of these components promotes excretion from the body excess liquid together with uric acid salts, and the second - to relieve pain and inflammation. Fullflex is biologically active additive(dietary supplement), and thanks natural composition, has virtually no contraindications. An exception is pregnancy and lactation, as well as age under 14 years, since there is no data on the use of the drug to treat these categories of patients. The price of Fullflex capsules is from 300 to 350 rubles per pack of 30 pieces, a tube of ointment (75 g) costs 150 rubles. Capsules are taken 3-4 times a day, one piece, half an hour after meals. They should be swallowed whole, without chewing, and washed down boiled water. The ointment is applied thin layer on the sore joint in the morning, before getting out of bed, and rub until completely absorbed. The course of treatment with both types of drugs for gout is one month;
Benemide is a drug for removing uric acid from the body, recommended for use with short breaks throughout the patient’s life. Tests have proven that the main thing active substance tablets (probenecid) is one of the most effective means to remove uric acid. The price of the drug is quite high - 2850 rubles. It is very important to follow the daily dosage of the medication. You need to start treatment with a dose of ½ tablet 2 times a day, gradually reaching one pill per day. After a month, verification tests are taken, and if necessary, the doctor makes adjustments to increase the dose. The maximum dosage is 4 tablets per day;
Flexen is available in the form of gelatin capsules, suppositories, gel for external use and solution for injection. The active substance of all four forms of the drug is Ketoprofen, which belongs to the group of NSAIDs - non-steroidal anti-inflammatory drugs. The price of candles is from 180 to 220 rubles, capsules are from 150 to 190 rubles (depending on their quantity in the package), the gel costs 150-195 rubles, injection solution– 190-230 rubles. The dosage of capsules taken after meals is from 2 to 6 per day, suppositories - 1-2 per day. Rub the ointment into the skin in the morning and at night, and do the same intramuscular injections. The course of treatment is prescribed individually in each individual case;

Blemaren has the effect of alkalizing urine, due to which its acidity drops and the level of urates in it decreases. The drug is effervescent tablets, packed in a plastic cylinder. Blemaren removes uric acid and dissolves uric acid kidney stones. Daily dosage medicines - 4 tablets, the price of which ranges from 700 to 100 rubles per pack of 80 pieces.

To the means mixed action includes the drug Allomaron, which simultaneously reduces the synthesis of uric acid and increases its excretion from the body. The active ingredients of the drug are allopurinol and benzobromarone. Daily dose for adults is 1 tablet per day. average price packs of 20 tablets – 280 rubles.

The existing uric acid in the blood, with its increased concentration, is very dangerous, as it leads to the development renal failure and gout (a disease that affects the joints). The only way to get rid of such complications is to remove the acid using various methods.

In this article we will talk in detail about how exactly uric acid is removed, and what medicines are used for this purpose. We'll also talk about what exactly it leads to increased concentration of this substance in the blood.

Uric acid is colorless, dense crystals that are poorly soluble in ethanol and water. However, dissolution of uric acid is possible in glycerin, sulfuric acid (hot only) and alkali solutions.

The mechanisms of its production vary from mammal to mammal. Specifically in humans and other primates it is the final product purine exchange. Uric acid is produced as a result of enzymatic oxidation of the so-called xanthine (under the direct influence of xanthine oxidase).

Not a large number of acid accumulates in brain tissue, liver and blood. Also minimal amount Uric acid is found in the urine and sweat of all mammals (including humans).

Due to the active participation of the enzyme purine, the rate of formation of uric acid increases significantly, which is why the disease hyperuricemia develops. Most often, the activity of the purine enzyme is caused by frequent and abundant consumption of purine-rich foods.

Functions and contents in the human body

In the human body, uric acid is a powerful stimulant of the central nervous system. nervous system. It inhibits the so-called phosphodiesterase, thereby improving the action of the hormones adrenaline and norepinephrine (epinephrine and, accordingly, norepinephrine). Simply put, uric acid enhances the effects of these hormones and prolongs (prolongs) their effects.

Uric acid also serves as an antioxidant substance that binds and destroys free radicals. That is, it helps cleanse the human nervous system of various toxic substances.

Uric acid in joints (video)

Reasons for increasing content

There are many reasons for the development of hyperuricemia. Unfortunately, not all of them can be prevented in advance (especially genetic ones).

In general reasons for increased uric acid levels the following:

weakening of the kidneys;
high consumption of fructose in food;
consumption of purine-rich foods;
frequent and plentiful consumption of high-calorie and fatty foods;
starvation;
metabolic diseases;
genetic predisposition;
long-term dietary food with limited consumption of carbohydrate foods;
metabolic diseases (endocrine pathologies).

Why is high uric acid dangerous?

Excessive amounts of uric acid in the tissues of the human body leads to the accumulation of salts and the development of various lesions joints and kidneys. Most often, the joints are affected by gout, which, if the developed hyperuricemia is not treated, subsequently leads to severe arthritis.

In general, hyperuricemia leads to development the following diseases (directly or indirectly, as additional factor) in humans:

Arthritis and gout of the joints.
Chronic inflammatory disease kidney
Ischemia of tissues of the abdominal organs.
Atherosclerosis.
Urolithiasis of the kidneys.
Metabolic syndrome.
Loesch-Nychen syndrome.
Kidney failure.
Long-term use of diuretics and aspirin.

Due to the constant deposition of salts in this disease, it is not certain segments of the joints that suffer, but all joints at the same time. That is, if the patient does not agree to remove salts and uric acid from the body, he should expect the development of total arthritis (including damage to the jaw joints).

IN initial stages hyperuricemia does not pose a danger, since it can be relatively easily stopped with the help of various means(including folk remedies that help). Lack of treatment in 98% of cases leads to severe disability of the patient or even death within 10 years.

Symptoms of increased content

Symptoms of increased uric acid levels are nonspecific and are often mistaken for completely different diseases. Hyperuricemia can only be reliably confirmed using laboratory tests.

Symptoms of High Uric Acid Levels the following:

sudden onset of arthralgia (joint pain);
muscle pain;
nervous tics;
bed-wetting;
increased sweating;
the occurrence of the above symptoms of biliary dyskinesia;
asthenic syndrome;
fever;
pain in the lumbar region.

Norms and analysis for uric acid content in the body

To determine the level of uric acid, it is enough to donate blood (or rather serum) for a biochemical analysis. In this case, blood sampling is carried out exclusively on an empty stomach (8-14 hours of fasting is sufficient).

Such research can be carried out at any private clinic or public hospital. Unfortunately, if we talk about public clinics, then this type biochemical analysis access is not everywhere. The cost of such a procedure is 200-400 rubles (depending on the region).

Normal uric acid test values for men are as follows:

age 12-60 years: 252-451 µm/l;
age 60-90 years: 244-471 µm/l;
age over 90 years: 205-491 µm/l.

Normal uric acid test values for women are as follows:

age 0-12 years: 118-324 µm/l;
age 12-60 years: 133-390 µm/l;
age 60-90 years: 204-430 µm/l;
age over 90 years: 128-450 µm/l.

Which doctor should I contact for help?

It is strictly prohibited to remove acid and salts on your own, without first consulting a doctor. This can not only result in zero effectiveness and a waste of time, but also in the progression of the disease and the development of serious complications.

The initial consultation about this pathology should be carried out with a general practitioner or endocrinologist. If complications have already developed, consultation with a nephrologist (specializing in kidney diseases) and a rheumatologist (specializing in joint diseases) may be required.

After consultation, you cannot prescribe medications yourself (including folk remedies). Treatment should be carried out exclusively according to the recommendations of doctors. Moreover, in the presence of drug treatment, it is advisable additional treatment folk remedies should also be discussed with your doctor.

If the doctor prohibits the use of folk remedies, then you should not use them secretly. The fact is that many traditional methods of treatment for such a disease are erroneous and may provoke increased formation of uric acid.

Dietary nutrition during the removal of uric acid involves a thorough review of the patient’s diet and the exclusion of many harmful products nutrition. Thus, they are removed from the patient’s menu for a long period of time. following products power supply:

red meat;
any legumes;
alcoholic drinks;
offal;
smoked meats;
restrictions on fried foods are being introduced;
table salt (it should be replaced with sea salt);
spicy seasonings;
sugar (it needs to be replaced with honey).

The diet of a patient with elevated uric acid levels should consist primarily of vegetable and fruit products. Porridge and berries should also be present; fasting is not allowed, as this in itself is the cause of hyperuricemia.

Drug treatment

Unfortunately, it is impossible to limit yourself to diet alone for hyperuricemia. The diet helps stop the flow of purine substances into the blood, but cannot cure an existing increase in their level.

For this purpose it is used drug treatment, capable of removing excess salts, purines and uric acid. Most effective drugs for the treatment of this disease are “Probenecid”, “Allopurinol” and “Blemaren”.

Probenecid removes urate from the blood plasma and cures the patient of gout (if any). The drug significantly accelerates the removal of acid from the blood, which not only treats the underlying disease, but also prevents acid deposition in the future.

Allopurinol reduces the production of urate in the body and significantly reduces the risk of gout. Treatment with this drug is long-term, sometimes exceeding 3 months.

Blemaren quickly normalizes uric acid metabolism and destroys uric acid stones. The huge advantage of Blemaren over the two previous drugs is that it does not affect the patient’s liver and kidneys and is the most safe medicine against hyperuricemia.

Traditional methods

Traditional methods of treating hyperuricemia are not independent therapy and only complement drug treatment. In this case, treatment with the help of folk remedies is allowed only after consultation with the attending physician.

One of the most effective ways remove uric acid by drinking a decoction lingonberry leaves. To do this, you need to add 200-250 grams of boiling water to 20 grams of leaves and let the broth brew for 30 minutes. You need to drink it three times a day, always with meals.

Nettle juice is also very effective. To prepare it, you need to squeeze the juice from recently picked nettles and consume a teaspoon immediately before meals. The juice is effective only for a day (even in the refrigerator), after which it loses its medicinal properties.

Birch leaves help some patients. So to a tablespoon of pre-crushed birch leaves you need to add about a glass boiled water. After this, you need to let the broth brew for one and a half to two hours and strain it. You need to drink an infusion of birch leaves twice a day with food, a quarter glass.

Uric acid is a substance produced by the breakdown of purines and proteins. This product is an antioxidant, activates and enhances the effect of adrenaline and neo-adrenaline. Excreted via the kidneys. If this organ does not work correctly and frequent use products that contain a large amount of purines, uric acid begins to concentrate in the blood and leads to an increase in hyperuricemia. This may put a person at risk of accumulation harmful salts in tissues and joints, which causes multiple violations in the work of organs.

To bring uric acid levels back to normal, need to follow a nutritious diet, take medications, use folk remedies and perform special therapeutic exercises. We will learn further about what the normal level of uric acid is in men and women, and how to reduce the content of this substance in the body as quickly as possible.

Norms

In men normal indicators uric acid is always higher than that of the fair sex. Age standards for men are shown in the table.

As seen, Great chance development of hyperuricemia in men after 50 years.

Normal levels of this substance in women under 60 years of age should not be more than 200-300 µmol/l, after 60 years – 210-430 , after 90 years – 130-460 µmol/l.

Why is it important to remove uric acid?

At maximum levels, uric acid forms salts - sodium urates. These substances are concentrated and cause the formation of tophi, the favorite places of which are:

outer part of the ear;
Feet;
Hands;
articular surfaces (ankle, elbow).

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Anna Poniaeva. Graduated from Nizhny Novgorod medical academy(2007-2014) and Residency in Clinical Laboratory Diagnostics (2014-2016).

Often, salts can accumulate in synovial pockets, which leads to the development of inflammation in the joints, pain, and limited movement.

Diseases that progress due to an increase in the concentration of uric acid in the body.

Arthritis.
Gout.
Stone formation in the kidneys and bladder.
Osteochondrosis.
Kidney failure.
Heart attack.
Rheumatism.
Arthrosis.

If the substance accumulates in brain tissue, it leads to memory loss, decreased intelligence, headaches, and stroke.

Women and men with excess acid levels often feel weak, irritable, fatigued, and prone to insomnia and neuroses.

Removal methods

If, after taking a blood test for biochemistry, a man or woman is found to have increased performance uric acid, this indicates that urgent measures need to be taken. Firstly, the doctor will recommend following a diet by removing foods with high content purines. Next, the patient is prescribed special diuretic drugs. It wouldn't hurt to resort to traditional methods treatment - drink infusions based on medicinal herbs, decoctions and tinctures.

Medicines

Taking medications is the main and mandatory stage in the treatment of gout.

It is worth noting that only compliance nutritious diet and conducting therapeutic exercises V in this case not enough.

To normalize the level of uric acid in the blood, you should find out the reason that provoked the accumulation of acid in the body. The main sources of increase this indicator is bad job kidneys, which slows down the excretion of salts.

Develop effective scheme treatment can only be done by a doctor based on laboratory tests, instrumental studies And external examination patient.

Gout- a disease associated with pathological change joints. The cause of gout is high level uric acid. The disease is characterized by acute painful attacks in the joints (most often in one of the thumbs legs), redness and swelling skin in the affected area. If the disease is not treated, erosion will form on the bone. The question of how to remove uric acid from the body, and what drugs help get rid of excessive amounts of urate in the blood, is decided taking into account the etiology of the disease.

Review of drugs for the treatment of gout that remove uric acid

For gout, it is recommended to help reduce purines, but remove uric acid only with the help proper nutrition impossible. Therefore, if symptoms of the disease appear, it is imperative to contact a specialist. Based on laboratory tests of the patient’s urine, the doctor prescribes appropriate therapy. There are 2 types of medications used to treat gout:

drugs that remove uric acid from the body;
drugs that reduce the concentration of uric acid in muscle and joint tissues.

Probenecid

Probenecid is one of the most commonly used uric acid-reducing drugs for gout. The medicine blocks the reabsorption of uric acid in the kidney tubules, thereby increasing its excretion. At chronic course initial diseases single dose is 250 mg taken twice a day. After a week, the dose is usually increased to 500 mg twice daily. When lack of effectiveness drug therapy the dosage can be increased, but it should be taken into account that the maximum daily dose does not exceed 2 g. Probenecid is a drug long-term use. In the absence of acute gouty attacks for 6 months, if, in addition, the urate concentration is normal, the dose is gradually reduced to the minimum amount.

Blemaren

One of the effective remedies in the treatment of gout is Blemaren. The drug normalizes metabolism, alkalizes the body, while uric acid stones gradually dissolve. A significant advantage is that Blemarin does not violate normal functioning kidneys and liver, which is why the medicine can be taken by pregnant and lactating women without risk to health. The daily dose is 2 – 6 tablets. Duration of treatment is up to 6 months. Before taking, the effervescent tablets are dissolved in a glass of liquid. It could be mineral water, fruit juice, compote or tea.

Allopurinol

Allopurinol is a drug that affects the synthesis, reducing its concentration in liquid media body, including in urine. The doctor determines the dosage of the medicine individually, taking into account the severity of the disease. The daily dose of Allopurinol can range from 100 mg to 900 mg. Frequency of administration – 2-4 times a day immediately after eating. The drug can be used in the treatment of children; 10-20 mg per 1 kilogram of the child’s weight is prescribed per day. Allopurinol is contraindicated for use during pregnancy and lactation. In addition, the drug should not be taken if there is severe dysfunction. thyroid gland, kidneys and liver. In case of decreased liver or kidney function, a reduction in the dosage of the drug should be considered.

We hope the material about which medications remove uric acid from the body will be useful if you have gout in an inactive stage. Remember that it is impossible to remove uric acid when the signs of the disease are already obvious.