Overdose of pills with fatal outcome. Consequences of hypertension for the body

How to take the medicine: before meals or after? Influence chemical composition food on the pharmacological activity of the drug. Medicines containing sugar (information for patients with diabetes mellitus). Can I take the drug with tea or milk?

Any medicine purchased at a pharmacy is accompanied by special instructions by application. But how often do we pay attention to this information? Meanwhile, compliance (or non-compliance) with the rules of administration can have a large, if not decisive, impact on the effect of the medicine. For most drugs this is due to processes occurring in gastrointestinal tract. Food, as well as gastric juice, digestive enzymes and bile, which are released during its digestion, can interact with medications and change their properties. That is why it is not at all indifferent when the medicine is taken: on an empty stomach, during or after a meal.

The doctor's instructions or recommendations contained in the instructions for use of the drug are determined mainly by known facts physiology of digestion. 4 hours after a meal or 30 minutes before the next meal (this time is called “fasting”), the stomach is empty, the amount gastric juice it contains minimal amounts (literally a few tablespoons). Gastric juice at this time contains little hydrochloric acid. As breakfast, lunch or dinner approaches, the amount of gastric juice and hydrochloric acid in it increases, and with the first portions of food its secretion becomes especially abundant. As food enters the stomach, the acidity of gastric juice gradually decreases due to its neutralization by food (especially if you eat eggs or drink milk). However, within 1-2 hours after eating, it increases again, since the stomach by this time is empty of food, and the secretion of gastric juice still continues. This secondary acidity is especially pronounced after consuming fatty foods. fried meat or black bread. Anyone who knows heartburn can attest to this. In addition, when using fatty foods its exit from the stomach is delayed, and it is even possible for pancreatic juice produced by the pancreas to flow from the duodenum into the stomach (so-called reflux).

Food mixed with gastric juice goes into primary department small intestine – duodenum. Bile produced by the liver and pancreatic juice secreted by the pancreas also begin to flow there. Due to the content of a large number of digestive enzymes in pancreatic juice and biologically active substances The active process of food digestion begins in bile. Unlike pancreatic juice, bile is secreted constantly, including between meals. Excessive amount of bile enters gallbladder, where a reserve is created for the needs of the body.

Knowing what happens to food in our stomach and intestines during the day, let's try to answer the question, when is it better to take medications: before, during or after meals?

If there are no other instructions in the instructions or in the doctor's prescription, it is better to take medications on an empty stomach, 30 minutes before meals, since interaction with food and digestive juices can disrupt the absorption mechanism or lead to changes in the properties of the medications.

Take on an empty stomach:

– all tinctures, infusions, decoctions and similar preparations made from plant materials. They contain a sum of active substances, some of which, under the influence of hydrochloric acid in the stomach, can be digested and converted into inactive forms. In addition, under the influence of food, the absorption of individual components of such drugs may be impaired and, as a result, insufficient or distorted action;

– all calcium supplements, although some of them (for example, calcium chloride) have a pronounced irritant effect. The fact is that calcium, when bound with fatty and other acids, forms insoluble compounds. Therefore, taking drugs such as calcium glycerophosphate, calcium chloride, calcium gluconate and the like during or after meals are at least useless;

- medications that, although absorbed when taken with food, for some reason have an adverse effect on digestion or relax smooth muscles. An example is a drug that eliminates or weakens spasms smooth muscle (antispasmodic ) drotaverine(known to everyone as No-shpa) and others;

Immediately after eating, it is better to take medications that irritate the gastric mucosa: indomethacin , acetylsalicylic acid , steroids , metronidazole , reserpine and others. To avoid the irritating effects of these drugs and calcium supplements, it is better to drink them with milk, jelly or rice water.

A special group consists of medications that should act directly on the stomach or on the digestion process itself. Thus, drugs that reduce the acidity of gastric juice ( antacids ), as well as means that weaken the irritating effect of food on a sore stomach and prevent copious discharge gastric juice, usually taken 30 minutes before meals.

10-15 minutes before meals, it is recommended to take drugs that stimulate the secretion of the digestive glands (bitterness), and choleretic agents . Gastric juice substitutes are taken with food, and bile substitutes (for example, Allohol) at the end or immediately after a meal. Medicines that contain digestive enzymes and help digest food are usually taken before meals, during meals, or immediately after meals. Drugs that suppress the release of hydrochloric acid into gastric juice, such as cimetidine should be taken immediately or soon after a meal, otherwise they block digestion at the very first stage. All multivitamin preparations are also taken with or immediately after meals.

Of course, there are drugs that act regardless of food intake, and this is usually indicated in the instructions.

However, not only the presence of food masses in the stomach and intestines affects the absorption of drugs. The composition of food can also change this process. For example, with a diet rich in fat, the concentration of vitamin A in the blood plasma increases (the speed and completeness of its absorption in the intestine increases). Fats, especially vegetable fats, reduce the secretion of gastric juice and slow down stomach contractions. Under the influence of foods saturated with fats, absorption and, accordingly, the effectiveness of action are significantly reduced. anthelmintic drugs , nitrofurans , sulfonamides . In the same time rich in fats food is recommended in cases where it is necessary to increase the absorption of fat-soluble drugs - anticoagulants , vitamins A, D and E, metronidazole , tranquilizers benzodiazepine group. Carbohydrates also slow down gastric emptying, which can interfere with the absorption of sulfonamides, antibiotics ( macrolides , cephalosporins ). Milk enhances the absorption of vitamin D, the excess of which is primarily dangerous for the central nervous system. Protein nutrition or consumption of pickled, sour and salty foods impairs the absorption of anti-tuberculosis drugs isoniazid, and protein-free, on the contrary, improves.

Of particular note are medicinal products containing sugar (sucrose, glucose) as a flavoring agent. In addition to the additional carbohydrate load (which, by the way, is small, given the small volume of the tablet or spoon of syrup), this is a potential source of danger for people with diabetes. Information about the sugar content of the drug is contained in the package insert and/or indicated on the packaging of the drug.

A change in acidity in the stomach can occur when taking medications with various fruits and vegetable juices, tonic drinks and dairy products. Tea contains tannin, which forms compounds with nitrogen-containing drugs that are indigestible by the body: papaverine, codeine, caffeine, aminophylline, amidopyrine, antipyrine, belladonna preparations, cardiac glycosides and others. If a person suffering from anemia takes iron supplements and washes them down with tea, the “tannin + iron” complex precipitates - therefore, the medicine is not absorbed. You should not drink sedatives or sleeping pills tea, because it stimulates the central nervous system. However, there are exceptions: vitamin C preparations can be taken with tea, which itself - like any plant - contains vitamin C. Tetracycline, doxycycline, metacycline and other tetracycline antibiotics cannot be taken with milk, since the calcium present in it, interacting with the drug, reduces it Effect. For the same reason, when treating with tetracyclines, you should avoid smoked meats and sausages. However, sulfa drugs are recommended to be taken with alkaline solution(For example, mineral water with a slightly alkaline reaction) to prevent kidney stone formation.

So, let's summarize. Cannot be combined :

• antibiotics of the tetracycline group, lincomycin, preparations containing caffeine (askofen, citramon, caffetin) - with milk, kefir, cottage cheese;
• iron supplements - with tea, coffee, milk, nuts, grain products;
• calcium supplements – with carbonated soft drinks and juices containing citric acid;
• erythromycin, ampicillin - with fruit and vegetable juices;
• sulfadimethoxine, sulgin, biseptol, cimetidine, theophylline - with meat, fish, cheese, legumes containing a lot of protein;
• aspirin and medications containing acetylsalicylic acid, furagin, 5-NOK - with butter, sour cream, fatty foods;
• paracetamol, sulfadimethoxine, biseptol, furosemide, cimetidine - with prunes, beets, sweet and flour dishes;
• sulfonamides: biseptol, etazol, sulfalene - with herbs, spinach, milk, liver, grain products;
• baralgin, analgin, panadol, spazgan, paracetamol, maxigan - with smoked sausages.

Literature

1. Anichkov S.V., Belenky M.L. Textbook of pharmacology. – MEDGIZ Leningrad Association, 1955.
2. Belousov Yu.B., Moiseev V.S., Lepakhin V.K. Clinical pharmacology and pharmacotherapy: A guide for doctors. – M.: Universum, 1993. – 398 p.
3. Karkishchenko N.N. Pharmacological basis of therapy: Guide and reference for doctors and students. – M.: IMP-Medicine, 1996. – 560 p.
4. Basic and clinical pharmacology/ Ed. Bertram G. Katzung; Per. from English edited by doc. honey. sciences, prof. E.E. Zwartau: In 2 volumes. – M. – St. Petersburg: Binom – Nevsky Dialect, 1998. – T. 1, 2.
5. Krylov Yu.F., Bobyrev V.M. Pharmacology. – M.: VUNMC Ministry of Health of the Russian Federation, 1999. – 352 p.
6. Kudrin A.N., Ponomarev V.D., Makarov V.A. Rational use medicines: “Medicine” series. – M.: Knowledge, 1977.
7. Modern medical encyclopedia. / Ed. R. Bercow, M. Birsa, R. Bogin, E. Fletcher. Per. from English under general editorship G.B. Fedoseeva. – St. Petersburg: Norint, 2001 – 1264 pp.: ill.
8. Kharkevich D.A. Pharmacology: Textbook. – 6th ed., revised. and additional – M.: GEOTAR MEDICINE, 1999. – 664 p.
9. RED BOOK and Drud Topics. – 106th ed. – Thomson Medical Economics, 2000. – 840 p.
10. Materials from the site www.AIF.ru.

At the same time, very often the reception is carried out without observing important rules, and therefore medications turn out to be useless, and even harmful. ABOUT important rules reception tells pharmacist with 50 years of experience in pharmacy Irina Dubonosova:

— My colleagues talked about a buyer who used rectal suppositories Orally, in other words, I washed them down with water. And he came to the pharmacy with a complaint: it didn’t help, they say. And another tried to insert a potency pill into an organ that needed help. An erection never happened, but I almost had to see a surgeon. Perhaps both cases are nothing more than an anecdote, but when purchasing medications, you must always read the instructions before use and follow them strictly.

Chew or suck?

Be sure to follow the prescribed method of use, otherwise there is a high risk that the active substance simply will not reach its destination. If the instructions for the drug say: “chewable tablet” - chew, “sucking” - suck, it says “put under the tongue” - put it. If it is not written: “bite”, “chew”, then be sure to swallow it whole with water. As a last resort, crush before swallowing, but only if the tablet is not coated. Otherwise, grinding will lead to poor absorption of the medication.

If there is no dividing line on the tablet, there is no need to break it - this means that a half dose is not intended for use. Do not pour out or pour out the contents of the tablet from the capsule - the medicine is specially placed in this form and not in any other form. This way it will be absorbed better and safer.

Shouldn't you take more than two?

It is better not to take several different medications at the same time. Especially if they are prescribed by different specialists. Of course, it is better to consult a doctor when prescribing a new medication, telling him which medications are already prescribed to you.

If you still accept different tablets turned out to be necessary, take them not one after another, but with a break of 30-60 minutes. For example: antibiotics should not be taken with antipyretics, sleeping pills, antihistamines. Iron supplements cannot be combined with antacids (Almagel, Maalox, Rennie, etc.). Oral contraceptives (Marvelon, non-ovlon, Janine, Tri-mercy, etc.) are incompatible with analgin, antibiotics and sulfonamides (streptocide, biseptol). Do not take papaverine and aspirin, vitamin C and penicillin, dibazole and tetracycline at the same time.

When treated with enterosorbents ( Activated carbon, polysorb, smecta) the break between them and other medications (any!) should be at least 2 hours.

If you are in doubt about how to take your medications correctly, try to get information from different sources.

What to drink with it?

Under no circumstances should you drink: tea, coffee, sweet juices, soda and, of course, alcoholic drinks.

You can almost always use plain water.

If the annotation does not say when to drink and what you can take the tablets with, it means that you can take them at any time, but it is better to do it 30-40 minutes before meals (or at least 15-20) and wash it down with cool water.

Drink or wait?

Consider your health status, age, occupation, and even gender when taking certain medications. Children, pregnant women, elderly people and drivers need to be especially careful when taking medications. Medicines such as erythromycin, verapamil, diazepam act less effectively on women than on men, but anaprilin and tazepam do the opposite.

Remember that there are many drugs that have the same principle of action, but have different names. This is due to the presence of numerous generics for most drugs. For example, paracetamol is sold as Panadol, Tylenol, Efferalgan, Aldolor, Milistan. Diclofenac - like dicloran, bioran, voltaren, etc. Tavegil - like clemastine, clonidine - like hemitone and catapresan. These are all analogue drugs.

It is important to know

Tablets in gelatin capsules must be taken standing or sitting and washed down with at least 100 ml of water, otherwise the gelatin capsule may stick to the wall of the esophagus.

It is better to take medications to lower blood pressure while lying down.

It is better to first drip the heart drops onto a piece of sugar.

Cough tablets like mucaltin work more effectively if they are dissolved in a small amount slightly sweet water and drink one hour before meals.

Caffeine, theobromine and theophylline can be washed down with sour juices.

Oral tetracycline preparations should be taken while standing and washed down with a glass of water.

Most multivitamins are absorbed regardless of meal time, but it is best not to take them with meals.

When taking antipyretic medications, try not to eat a lot of dairy and plant foods, but temporarily switch to meat products.

Bad habits

Alcohol enhances the effect of medications containing paracetamol and antihypertensive drugs- if you take phenobarbital and drink it with alcohol, there is a risk of dying from respiratory arrest.

Alcoholic drinks combined with aspirin can cause stomach ulcers and stomach bleeding.

A cocktail of alcohol with antidepressants, sleeping pills or antiallergic drugs enhances the calming effect of these drugs, and a person who takes this mixture greatly risks not only his health, but also the lives of others - for example, if he gets behind the wheel in this state.

The most unpredictable drugs Antibiotics; many antiallergic and antifungal agents; sleeping pills(especially oxazepam and diazepam); antidepressants (especially tricyclics and from the group of MAO inhibitors); paracetamol; statins; cimetidine, omeprazole and other so-called. inhibitors proton pump; cyclosporine; cisapride; warfarin.

Alcohol mixed with nitroglycerin leads to sharp decline pressure, which can lead to fainting.

Insulin and other antidiabetic drugs in combination with alcoholic beverages severely lower blood sugar, which can also cause fainting.

Violation heart rate There is a risk of drinking alcohol simultaneously with diuretics and digoxin, as it provokes a change in potassium balance.

Nicotine makes it less effective treatment psychotropic, cardiovascular drugs, pulmonary inhalers and even reduces the effect of birth control pills.

Remember

Despite the advice stated above, always carefully read the instructions for medications, consult with your doctor and listen to the sensations of your own body. When self-medicating, you are fully responsible for possible Negative consequences for your health.

“Never, under any circumstances, take sleeping pills at the same time as a laxative...”
Colin Hoover

To achieve the necessary therapeutic effect From the treatment being carried out, first of all you need to correctly follow the instructions of your attending physician!

1) Before you accept necessary medicine, carefully read the doctor’s prescription or the attached instructions for use of the drug. Please pay Special attention on the:
● dose recommended for a single dose;
● on the number of medication doses per day;
● during the reception;
● on the method of administration;
● the duration of the course of treatment.

All this is very important both to obtain the necessary therapeutic effect and to reduce the likelihood of side effects of the drug.

Remember that when prescribing a medicine 2 times a day, the word “day” does not mean the light part of the day, but all 24 hours, since our body works around the clock! Therefore, taking pills should be divided into equal periods of time if possible. This is especially true for antimicrobial agents, because microbes work without a break for lunch and sleep. That is, with a two-time dose, the interval between taking each dosage should be 12 hours, three times - 8 hours, four times - 6 hours.

2) Information about when to take the medicine is also important: on an empty stomach, during meals or some time after it.

Some medications are designed to be absorbed in the stomach and intestines, while others are only absorbed in the intestines. For some drugs, the time of administration and its relationship with food intake may not matter. This is due to the processes occurring in the gastrointestinal tract. Food, as well as gastric juice, digestive enzymes and bile that are released during its digestion, can interact with medications and change their properties. That is why it is not at all indifferent when the medicine is taken: before meals, during meals or after it.

Taking the tablets “before meals” means on an empty stomach, that is, no earlier than 2-3 hours after the last meal and no later than 20 minutes before meals.

Taking medication “with meals” often does not raise any questions. But it's worth keeping in mind that the word "meal" doesn't have to mean a three-course meal. If taking the pills coincides with breakfast, lunch or dinner, that’s good, but if not, tea with crackers or a glass of milk will be enough.

How to take pills “after meals”? This needs to be sorted out. Immediately after eating, medications that irritate the stomach are usually taken, and 2 hours after eating, medications that reduce stomach acidity are usually taken.

Of course, there are drugs that act regardless of food intake, and this is usually indicated in the instructions.

3) One more important point- What should you take with your medications? Remember, dear readers, there is a category of food products that can seriously affect the effectiveness of the medications used. Here are some examples:

● grapefruit juice does not mix well with medications. Back in 2000, scientists proved that it should not be used simultaneously with heart medications. The fact is that grapefruit juice contains a substance that can interact with certain medications, increasing the rate of their absorption in the patient’s gastrointestinal tract;

● tea contains tannin, which forms compounds with drugs that are not absorbed by the body. If a person suffering from anemia takes iron supplements and washes them down with tea, the “tannin + iron” complex precipitates, therefore, the medicine is not absorbed and the effectiveness of the drug is reduced to zero;

● tetracycline antibiotics (tetracycline, doxycycline, etc.) should not be taken with milk, since the calcium present in it, interacting with the drug, reduces its effect. For the same reason, when treating with tetracyclines, you should avoid smoked products.

But there are exceptions: it is recommended to take sulfonamide drugs with an alkaline solution (for example, slightly alkaline mineral water) to prevent kidney stones.

It is better to make it a rule to take 100 ml of medicine boiled water room temperature!

Remember!

Anything that is “clad” in a shell or capsule should not be chewed or bitten. It is recommended to chew chewable tablets thoroughly; suckable tablets should be dissolved. The release form of the drug is selected not for beauty or even for the convenience of the patient, but based on the pharmacokinetics and pharmacodynamics of the drug, that is, for the best therapeutic effect.

Many medications interact with each other, so try to alternate medications if possible. Antibiotics are often incompatible. They should not be unnecessarily combined with antipyretics, hypnotics, and antihistamines. And, of course, in no case with alcohol.

Never supplement your doctor’s prescriptions with what you think are “useful” medications that “strengthen the immune system,” “protect the liver,” “accelerate recovery from colds,” or herbal infusions. Always express your wishes to your doctor and coordinate all innovations with him.

Dear people of Kazakhstan, value your life, your health and the health of your loved ones! Be responsible, do not use medications without a doctor's prescription! Remember: only a doctor can determine the need to take a particular drug.

If you have any questions about the use of medications, call the toll-free Call Service: 8 800 080 88 87

Drug Information and Analytical Center Republican state enterprise on the right of economic management "Republican Center for Health Development" of the Ministry of Health and social development Republic of Kazakhstan.

When prescribing taking pills several times a day, most doctors mean by this a day, i.e. 24 hours. Internal organs work around the clock, bacteria work in the same way without rest or sleep. Therefore, medications should be taken at equal intervals, especially for antimicrobial agents.

With short-term courses of medication it is easier, because for a couple of days you can adhere to all the rules, but with long-term courses certain difficulties often arise. A person takes a pill, and then forgets and takes a second one “just in case.” It's good if the medicine is not strong. There are a lot of methods to combat such forgetfulness, everyone chooses for themselves: some people use ticks on the calendar, others put medications in a visible place, some set alarm clocks and set reminders on their mobile phones, etc. Pharmacological companies produce special calendars in which you can mark each appointment.

Before or after meals

All medications, according to their connection with meals, are divided into groups: “anyway,” “before,” “after,” and “during meals.” At the same time, in the doctor’s mind, the patient eats according to a schedule, without snacking during breaks, and the patient is sure that the eaten apple or pie has nothing to do with food.

A medicine prescribed to be taken “before meals” assumes that the person did not eat anything before taking it and will not eat anything for at least the specified period after eating. The tablet should be taken into an empty stomach so as not to be exposed to gastric juice, food components, etc. V in this case a glass of juice or candy two hours or an hour before taking the medicine can dramatically affect the result of treatment. There are cases when you need to eat exactly at the specified appointment time, so it is advisable to clarify what exactly the doctor means.

“With food” is the easiest way to take it, but if your diet is far from ideal, it is better to ask your doctor which foods are preferable while taking a particular medication.

Drugs that are prescribed “after meals” include drugs that irritate the gastric mucosa or help normalize digestion. In this case, a small amount of food will be enough.

Rules for taking medications

Most medications must be taken separately. This is not very convenient, but swallowing tablets by the handful can produce unpredictable effects; at least half an hour should pass between doses.

Also, keep in mind that vitamins, combined agents from colds, herbs and hepatorrotectors during treatment should be taken only after consultation with your doctor.

Not every tablet can be divided into several doses; some drugs are coated, damage to which can significantly affect the properties of the drug. The absence of a dividing strip on the tablet most often indicates that it is prohibited to divide it.

With rare exceptions, medications are taken only with water, plain and not carbonated. The exception is certain drugs, which need to be washed down with sour drinks, milk, mineral water or other separately specified liquids, the rules of administration are most often specified in the instructions.

Methods of taking drugs also have great importance, For example, chewable tablet, which you swallowed whole, will take effect after a completely different time or will not produce any therapeutic effect at all.

The release form of the drug should also be taken into account. If the tablet has a special coating, then it cannot be crushed or bitten, because its main covering function is to protect, for example, the stomach, esophagus or tooth enamel from active substance. The encapsulated form indicates that the main medicinal substance should be absorbed into the body only in the intestines after a certain period of time, so they should not be opened.

According to world statistics, a quarter of all patients ARE HOSPITALIZED in connection with wrong technique medicines, not due to illness. More than 1/5 of drug complications are associated with drug interactions. We'll talk about how to take medications correctly in this article.

The body's sensitivity to drugs (drugs) is directly proportional to the number of tablets taken. Taking three at the same time medicines leads to the development of adverse (toxic-allergic) reactions in every fifth patient, and if you take more than five drugs (without a doctor’s prescription), then the likelihood of developing side effects increases four times!

Do not forget that medications also include vitamins, which many people buy in pharmacies to “feed” their body.

In addition, many people often use painkillers, sedatives, antipyretics for the purpose of self-medication, leading the body to toxic reactions (with the development skin manifestations up to eczema, kidney and liver failure), and, as a result, they enter critical condition V intensive care units clinical hospitals.

The effect of medications and their effectiveness largely depend on the timing of meals.

Medicines should be taken only after being prescribed by a doctor. Since in this situation we take into account accompanying illnesses, previously available allergic reactions, age and drug interactions.

It should be remembered that it is PROHIBITED to self-medicate!!!

Treatment will be effective and successful if the following RULES are observed:

How to take medications correctly

1. If you are prescribed medications, follow the recommendations of a specialist according to the scheme taking medications. Pay attention not only to the expiration date, dosage and frequency of administration per day, but also to the time instructions eating.

2. Medicines are necessary wash down with water. Many drugs are incompatible with a number of products, for example:

• milk and dairy products significantly reduce the effectiveness of antibiotics taken to treat respiratory and sexually transmitted infections;
• alcohol enhances the effect of antipyretic drugs (paracetamol), sedatives and cardiovascular drugs. Alcohol affects the bioavailability of almost all drugs;
• orange and grapefruit juice strengthen side effects medicines;
• tea and coffee help reduce the effectiveness of drugs;
• mineral water complicates the absorption of drugs.

3. Do not chew the coated tablets. Swallow the capsules whole, as the stomach contains hydrochloric acid, which destroys the medicine without the capsule and it will not have any effect therapeutic effect. And if there is a capsule, the drug reaches the intestines, where, when absorbed, it has a therapeutic effect.

4. Remember that it is not advisable to take more than three medications. Vitamins, herbs, biological supplements(dietary supplements) are also medications. Do not self-medicate!!!

5. Often lead to toxic effect on the body antipyretics, sedatives, painkillers, some antibiotics and non-steroidal anti-inflammatory drugs (brufen, voltaren, ortafen...).

Below is a table with some medications that are often used in treatment and how to take them.

List of medications and rules for taking them

	Name of the drug	Time of receipt	Note
	ANTIBACTERIAL drugs	On an empty stomach, 30-40 minutes before meals or in between meals.
	ANTIHELMINTHIC (anthelminthic) drugs		Eliminate fats from food
	ANTIANEMIC drugs	30 minutes before meals	Increase consumption of foods from high content iron (strawberries, apricots, apples, beets, pomegranates) in combination with ascorbic acid.
	ANTIDEPRESSANTS (MAO inhibitors)	Between meals, preferably at night	Exclude cheeses, feta cheese, cream, coffee, beer, wine, peanuts, bananas, beans, and beans from food. Recommended consumption vegetable dishes(salads, soups, stews).
	ANTICOAGULANTS	On an empty stomach, 30-60 minutes before meals
	ACETYLSALICYLIC ACID (aspirin)	Strictly after meals	Eliminate fats and spicy foods
	GLUCOCORTICOSTEROIDS drugs-hormones(cortisone, prednisolone, dexamethasone, triamcinolone, etc.)	Strictly after meals, drink milk.	Eat protein, calcium, potassium, vitamins, and dairy products.
	HORMONAL CONTRACEPTIVES (birth control)	Once a day, at the same time, with a drink a small amount water	Anticonvulsants, antituberculosis, antibacterial drugs(ampicillin, tetracycline). When using Yarina, you should stop smoking. It is necessary to monitor the blood coagulation system.
	DIURETICS (furosemide, lasix...) - diuretics	On an empty stomach in the morning
	CARDIAC GLYCOSIDES (preparations of foxglove, adonis, lily of the valley, oleander)	On an empty stomach, for dyspeptic symptoms - after meals	Eliminate protein foods
	30 minutes before meals	Limit easily digestible carbohydrates, alcohol, animal fats
	ANTACIDS (almagel, phosphalugel)	Inside, you can pure form or before taking, dilute in half a glass of water. Before meals, 40 minutes after meals and at night (as prescribed by a doctor)	Antibiotics of the tetracycline group, iron supplements, cardiac glycosides should be taken no earlier than two hours after taking these drugs
	IRON PREPARATIONS	During or after meals	Avoid milk and foods containing phytin (nuts, wheat, oatmeal), tea, red wine, coffee
	CALCIUM GLUCONATE	Before meals, drink water	Avoid products containing oxalic and acetic acids.
	CALCIUM CHLORIDE	After meal	Slows down the absorption of tetracyclines, digoxin, oral medications Fe (the interval between doses should be at least two hours). When combined with thiazide diuretics, it can increase hypercalcemia, reduce the effect of calcitonin in hypercalcemia, and reduce the bioavailability of phenytoin.
	Expectorant (bromhexine)	Before meals or - for dyspepsia - after meals	Bromhexine is not used simultaneously with medicines containing codeine, as this makes it difficult to cough up liquefied sputum.
	MUKALTIN ​​- expectorant	30-60 minutes before meals, dissolve in 1/3 glass of water
	NITROGLYCERIN, NITRATES (isoket, cardiquet) - cardiovascular drugs	Under the tongue or inside, regardless of food intake	With simultaneous use of ACE inhibitors and beta blockers, the hypotensive effect is enhanced. At simultaneous use with heparin the effect of the latter is reduced
	Proton pump INHIBITORS (Omeprazole, Omez) - drugs for the treatment of the gastrointestinal tract	Orally, capsules are usually taken in the morning, they cannot be chewed, they should be washed down with a small amount of water (immediately before or during meals)	Before starting therapy, it is necessary to exclude the presence of a malignant process (especially with a stomach ulcer), because treatment, masking symptoms, can delay the correct diagnosis
	POTASSIUM preparations (potassium orotate, asparkam, panangin)	Strictly after meals, drink with water	Reduces the effectiveness of cardiac glycosides. Potassium-sparing diuretics and ACE inhibitors increase the risk of hyperkalemia. Contraindicated in chronic renal failure
	ANTI-TUBERCULOSIS drugs	Appointment hours as prescribed by the doctor
	SULFANAMIDE drugs	30-40 minutes before meals, plenty of alkaline drink(2-3 liters of liquid per day)	Avoid foods containing sulfur (eggs) folic acid(beans, tomatoes, liver), fats and proteins
	ENZYMES (festal, mezim, panzinorm, creon)	During or immediately after eating. Swallow whole, do not chew
	ACE INHIBITORS (Renitec, enalapril..) - antihypertensive drugs, cardiovascular drugs	Taken regardless of meals	It is necessary to limit salt intake
	BETA BLOCKERS (egilok...) - antihypertensive drugs, cardiovascular drugs	Taken regardless of food intake	Affects the ability to drive, alcohol is prohibited, salt restriction is required
	ANGIOTENSIN II RECEPTOR (AT1 type) ANTAGONISTS (Lozap) - cardiovascular drugs	The drug is taken regardless of meals; The tablet is swallowed without chewing, washed down with water	The use of the drug may adversely affect activities that require a high speed of mental and physical reactions (for example, managing vehicles, maintenance of machines and mechanisms, work at height)
	CALCIUM ANTAGONISTS (isoptin, verapamil...) - antihypertensive, cardiovascular drugs	After meal
	ERGOCALCEFEROL (vitamin D2)	After meal	Combine with a diet containing a large number of vegetables and fruits

Monitor the expiration dates of medications and remove them promptly. from home first aid kit expired!!!

Contact your doctor in a timely manner to prescribe treatment, do not resort to self-medication, do not follow the advice of neighbors and acquaintances!!!